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beta-Sitostanol 83-45-4图1

beta-Sitostanol 83-45-4

2020-03-09 13:57970询价
价格:未填
品牌:上海惠诚生物
发货:3天内
发送询价
Cat. Number
1113
Chemical Name
beta-Sitostanol
CAS Number
83-45-4
Mol. Formula
C29H52O
Mol. Weight
417
Qty 1
50mg
Appearance
solid
Application Notes
98+%/97+%,98+% by TLC, 97+% by GC
Synonym
beta-Sitostanol,Stigmastanol
Solubility
chloroform
Storage condition
-20℃
References

Application Notes:

beta-Sitostanol is a plant stanol often found in small amounts in plant oils and is the fully hydrogenated product of betasitosterol. 1 Plant stanols and sterols have been used extensively in humans to attempt to lower cholesterol absorption and treat certain cancers.2 When plant sterols are consumed by animals in large quantities they can be absorbed by the gut leading to a dysfunction of metabolism and resulting in sitosterolemia, a high plasma plant sterol concentration, but stanols are not normally absorbed and are therefore preferred as cholesterol lowering agents.3 Plant stanols and sterols are important components of plant cell membranes and have a particular role in the plasma membrane, mitochondrial outer membrane, and endoplasmic reticulum. Plant sterols will complex with glycosphingolipids in raft-like sub-domains and can affect many cellular functions including membrane fluidity, permeability, activity of membrane-bound enzymes, cellular differentiation, cellular signaling, and cellular proliferation. They can be esterified, glycoslilated, and acylated to form steryl esters, steryl glycosides, and acylated steryl glycosides. Sterol esters are usually found only in small amounts naturally while sterol glycosides account for most of the common plant sterols.

References: 
1. M. Ramadan, R. Zayed, and H. El-Shamy “Screening of bioactive lipids and radical scavenging potential of some solanaceae plants” Food Chemistry, vol. 103 pp. 885-890, 2007 
2. A. de Jong, J. Plat, R. Mensink “metabolic effects of plant sterols and stanols (Review)” Journal of Nutritional Biochemistry, Vol. 14:7 pp. 362-369, 2003 
3. H. Gylling et al. “Serum and lipoprotein sitostanol and non-cholesterol sterols after an acute dose of plant stanol ester on its long-term consumption” European Journal of Nutrition, DOI: 10.1007/s00394-011-0249-5, 2011

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