品牌:上海惠诚生物
发货:3天内
| Cat. Number |
1049
|
| Chemical Name |
硫苷脂 Sulfatides
|
| CAS Number |
85496-63-5
|
| Mol. Formula |
C42H80NNaO11S
|
| Mol. Weight |
830 (stearoyl) Na+ Salt
|
| Qty 1 |
50mg
|
| Appearance |
solid
|
| Application Notes |
98+%,TLC; identity confirmed by MS
|
| Synonym |
硫苷脂 Sulfatides,
|
| Storage condition |
-20℃
|
| References |
Application Notes: Sulfatide is a type of sulfolipid that is found primarily in the central nervous system and is a myelin-specific sphingolipid. A deficiency of sulfatide in white and gray matter has been associated with Alzheimer’s disease and other types of dementia. Apoliprotein E plays an important regulating role in the metabolism of sulfatides.1 A production of anti-sulfatide antibodies in the cerebrospinal fluid, leading to a deficiency in sulfatides, may be a cause of degeneration of the myelin sheath, leading to multiple sclerosis.2 metachromatic leukodystrophy is an inherited disorder characterized by a deficiency of the lysosomal enzyme arylsulfatase A and the subsequent accumulation of sulfatide in neural and visceral tissues.3 An immunomodulatory role for sulfatides has been suggested in the pathogenesis of tuberculosis.
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