Phosphatidylinositol 4-phosphate, dipalmitoyl

H1919-1

Phosphatidylinositol 4-phosphate, dipalmitoyl, (NH4+salt) (DPPI-4-P)

synthetic

C₄₁H₇₇O₁₆P₂•3NH₄

942

1mg

solid

98+% 1H NMR, 31P NMR

DPPI-4-P; PI-4-P dipalmitoyl,(NH4+salt)

methanol, chloroform/methanol/DI water, 4:3:1; slightly soluble in water

-20°C

1. J. Zhang et al. “Role of Type I Phosphatidylinositol-4-Phosphate 5-Kinase in Insulin Secretion, Glucose metabolism, and Membrane Potential in INS-1
-Cells” Endocrinology, Vol.150(5) pp. 2127-2135, 2008
2. P.W. Majerus, “Inositol phosphate biochemistry” Annual Review of Biochemistry Vol. 61 pp. 225-250, 1992
3. Ao-Lin Hsu, et al. “Novel Function of Phosphoinositide 3-Kinase in T Cell Ca2+ Signaling: A Phosphatidylinositol 3,4,5-Trisphostphate-Mediated Ca2+ Entry Mechanism” Journal of Biological Chemistry May, Vol. 275 pp. 16242-16250, 2000
4. H. Shimamura, et al. “The PI3-kinase-Akt pathway promotes mesangial cell survival and inhibits apoptosis in vitro via NF-kappa B and Bad” Journal of American Society of Nephrology Vol. 14 pp. 1427-1434, 2003