N-二十四酰植物鞘胺醇

H2036

N-二十四酰植物鞘胺醇 N-Tetracosanoyl-phytosphingosine

semisynthetic

C₄₂H₈₅NO₄

668

5mg

solid

98+% TLC, MS

N-C24:0-Phytoceramide; N-Lignoceroyl-phytosphingosine

chloroform/methanol,5:1

-20°C

1. K. Ryu et al. “Anti-scratching Behavioral Effects of N-Stearoylphytosphingosine and 4-Hydroxysphinganine in Mice” Lipids, Vol. 45 pp. 615-618, 2010
2. M. Park et al. “Suppression of Extracellular Signal-related Kinase and Activation of p38 MAPK Are Two Critical Events Leading to Caspase-8- and Mitochondria-mediated Cell Death in Phytosphingosine-treated Human Cancer Cells” Journal of Biological Chemistry, Vol. 278, pp. 50624-50634, 2003
3. F. Omae et al. “DES2 protein is responsible for phytoceramide biosynthesis in the mouse small intestine” Journal of Biochemistry, vol. 379 pp. 687-695, 2004