N-十六酰植物鞘氨醇 N-Hexadecanoyl-phytosphingosine

H2035

N-十六酰植物鞘氨醇 N-Hexadecanoyl-phytosphingosine

semisynthetic

C₃₄H₆₉NO₄

556

5mg

solid

98+% TLC, GC

N-C16:0-Phytoceramide; N-Palmitoyl-phytosphingosine

chloroform/methanol, 5:1

-20°C

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2. F. Omae et al. “DES2 protein is responsible for phytoceramide biosynthesis in the mouse small intestine” Journal of Biochemistry, vol. 379 pp. 687-695, 2004
3. M. Sekiya et al. “A phytoceramide analog stimulates the production of chemokines through CREB activation in human endothelial cells” Int Immunopharmacol., vol. 11 pp. 1497-503, 2011
4. J-C. Jung et al. “Phytoceramide Shows Neuroprotection and Ameliorates Scopolamine-Induced Memory Impairment” Molecules, vol. 16 pp. 9090-9100, 2011