D,L-erythro-Dihydrosphingosine 3102-56-5

H1324

D,L-erythro-Dihydrosphingosine (Inhibitor of Sphingosine Kinase)

3102-56-5

synthetic

C₁₈H₃₉NO₂

301

25mg

solid

erythro 77%; threo 23% TLC, GC

D,L-erythro-Sphinganine, C18 chain

chloroform, ethanol, methanol, DMSO

-20°C

1. H. Fyrst et al. “Characterization of free endogenous C14 and C16 sphingoid bases from Drosophila melanogaster” Journal of Lipid Research, vol. 45 pp. 54-62, 2004
2. W. Zheng “Fenretinide increases dihydroceramide and dihydrosphingolipids due to inhibition of dihydroceramide desaturase” Georgia Institute of Technology, 2006
3. L. van der Westhuizen et al. “Sphingoid base levels in humans consuming fumonisin-contaminated maize in rural areas of the former Transkei, South Africa: a cross-sectional study” Food Additives and Contaminants, Vol. 25(11), pages 1385 – 1391, 2008
4. Shih-Hsuan Hsiao et al. “Effects of Exogenous Sphinganine, Sphingosine, and Sphingosine-1-Phosphate on Relaxation and Contraction of Porcine Thoracic Aortic and Pulmonary Arterial Rings” Toxicological Sciences, Vol. 86(1) Pp. 194-199, 2005