N-二十三酰神经酰胺三己糖苷上海惠诚进口

H1524

N-二十三酰神经酰胺三己糖苷 N-Tricosanoyl ceramide trihexoside

semisynthetic

C₅₉H₁₁₁NO₁₈

1122

0.5mg

solid

98+% TLC

N-C23:0-Ceramide trihexoside; N-Tricosanoyl globotriaosylceramide

DMSO, hot methanol, chloroform/methanol, 2:1

-20°C

1. S. Ashkenazi, and T. Cleary, “Rapid method to detect shiga toxin and shiga-like toxin I based on binding to globotriosyl ceramide (Gb3), their natural receptor.” J Clin Microbiol., Vol. 27:6 pp. 1145-1150, 1989
2. S. Bekri, et al. "The role of ceramide trihexoside (globotriaosylceramide) in the diagnosis and follow-up of the efficacy of treatment of Fabry disease: a review of the literature" Cardiovasc Hematol Agents Med Chem, Vol. 4:4 pp. 289–297, 2006
3. J. Groener, et al. “HPLC for simultaneous quantification of total ceramide, glucosylceramide, and ceramide trihexoside concentrations in plasma” Clin Chem., Vol. 53:4 pp. 742-747, 2007
4. K. Mills, A. Johnson, B. Winchester, “Synthesis of novel internal standards for the quantitative determination of plasma ceramide trihexoside in Fabry disease by tandem mass spectrometry” FEBS Lett., Vol. 27 pp. 171-176, 2002
5. C. Menge, et al. “Globotriaosylceramide (Gb(3)/CD77) is synthesized and surface expressed by bovine lymphocytes upon activation in vitro” Vet Immunol Immunopathol., Vol. 83 pp.19-36, 2001