N-Dodecanoyl-NBD-phytosphingosine惠诚进口

H1627-001

N-Dodecanoyl-NBD-phytosphingosine

semisynthetic

C₃₆H₆₃N₅O₇

678

1mg

solid

98+% TLC

N-C12:0-NBD-Phytoceramide; N-C12:0-NBD-Phytosphingosine

methanol, chloroform/methanol, 2:1

-20°C

1. C. Yuan et al. “CDase is a pan-ceramidase in Drosophila” Mol. Biol. Cell, vol. 22 pp. 33-43, 2011
2. Z. Mao et al. “Alkaline Ceramidase 2 (ACER2) and Its Product Dihydrosphingosine Mediate the Cytotoxicity of N-(4-Hydroxyphenyl)retinamide in Tumor Cells” The Journal of Biological Chemistry, vol. 285 pp. 19078-19090, 2010
3. M. Park et al. “Suppression of Extracellular Signal-related Kinase and Activation of p38 MAPK Are Two Critical Events Leading to Caspase-8- and Mitochondria-mediated Cell Death in Phytosphingosine-treated Human Cancer Cells” Journal of Biological Chemistry, Vol. 278, pp. 50624-50634, 2003
4. F. Omae et al. “DES2 protein is responsible for phytoceramide biosynthesis in the mouse small intestine” Journal of Biochemistry, vol. 379 pp. 687-695, 2004